Perkasie is a borough in Bucks County, Pennsylvania, 35 miles north of Philadelphia. Establishments in the borough early in the twentieth century included silk mills, baseballs, brickyards, lumber mills, tile works, a stone crusher, and manufacturies of cigars, tags and labels, wire novelties, etc. The population in 1900 was 1,803; in 1910, 2,779 people lived in Perkasie. The population was 8,828 at the 2000 census. Perkasie is part of Pennridge School District.

According to the United States Census Bureau, the borough has a total area of 2.6 square miles, of which, 2.6 square miles of it is land and 0.38% is water.
Perkasie is bordered by: East Rockhill, West Rockhill, Sellersville, and Hilltown.
Perkasie is home to a former major league baseball factory, now out of business. Between 1920 and 1950, the factory produced millions of baseballs through the Hubbert/Spalding contract. The factory still stands today, at 815 Chestnut Street, but has been converted into the Senior Citizens Center. The Pearl S. Buck House at Green Hills Farm, a registered National Historic Landmark, is located near Perkasie.
The Perkasie borough's nearest airport is located just north of the center of town, and is actually just on the other side of the East Rockhill Township border. Pennridge Airport is a public general aviation airport with one 4,200-foot long runway.
Perkasie was once served by the Bethlehem Branch of the Reading Railroad. That main line is now owned by SEPTA, however, passenger service was terminated in the early 1980s. It is still used by CSX and the East Penn Railroad for freight. Proposals for reactivating the line to provide passenger service have been discussed since the 1990s.
Perkasie is bordered by a state road on each side: PA 563 to the north; PA 313 to the east; PA 113 to the south; and PA 309 to the west. PA 152 runs right through the middle. I-476, I-276, and I-78 are the nearest interstates.
On June 26, 1988, about 15 percent of the town, including many historic buildings, was burned down in what became known as The Great Perkasie Fire. This massive fire was started by two 12-year-old boys who were playing with a lighter near the coal bins behind the Shelley & Sons lumberyard at Seventh and Market Streets. The fire was fought by about 300 firefighters who came from over 50 fire companies in three counties. Among the historic buildings lost were the American House and the Moyer-Kantner Funeral Home, both dating from 1870, and the Herstine Building. Despite the size of the fire, no fatalities were reported.
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